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Module -V
                Biological Warfare
                                                                                                    Warfare and
                     conditions for a long period extending to years. The bacteria, which form spores,  Its Types
                     are also known as persistent BW agents. Bacillus anthracis, cause of anthrax, is
                     a very important BW agent, which produces spores.
               (b)   Rickettsia: These are primarily parasites of insects and appear only secondary
                     in man and other animals. The microorganisms characteristically inhabit the cell
                     lining of the intestines and other tissues of the insects. They are found in a certain
                                                                                                Note
                     group of blood sucking insects, such as fleas, mites, lice and ticks. The rickettsia
                     causes no injury to the insects but is often pathogenic to men and other animals.
                     Some rickettsia cause diseases that are severe and often fatal. They are susceptible
                     to antibiotic treatment. They grow only within living cells like viruses.

               (c)   Viruses: A virus is a small infectious agent that replicates only inside the living
                     cells of other organisms. Viruses can infect all types of life forms, from animals
                     and plants to microorganisms, including bacteria. Viruses are not cellular and
                     therefore do not possess typical structures of a cell. No specific treatment is
                     available against viruses; viruses do not respond to antibiotic treatment. However
                     vaccination is effective. e.g. Small Pox
               (d)   Fungi: A fungus (plural - fungi) is any member of the group of organisms that
                     includes microorganisms such as yeasts and molds. The most common example
                     is mushrooms. Fungi may be regarded as primitive plants that do not produce its
                     own food. They draw nutrition from decaying vegetation matter. Most fungi can
                     exist either in a yeast-like state or as resistant spores. The fungi which produce
                     toxins (mycotoxins) are important BW agents.

               13.2.2 Essential Characteristics of BW Agents

               A majority of BW agents employ germs. Some of these organisms can only grow and
               reproduce under suitable conditions and they are regarded as non-persistent as they
               are extremely susceptible to variation in temperature, humidity and sunlight. Some
               agents, such as anthrax, are highly resistant to climatic effects and can be classified as
               persistent. Some important and essential characteristic BW agents are: -

               •     Infectivity: The infectivity of microorganisms is defined as its ability to cause
                     disease. A greater infectivity means that fewer microorganisms are required. It
                     means how fast the microorganisms can enter the body of the target.
               •     Virulence: The infective penetration of sufficient microorganism may produce

                     diseases of different severity. The most virulent strain produces the most acute
                     or severe effects and is a better BW agent.
               •     Incubation: The incubation period is the time between the infective penetration
                     of sufficient microorganisms into the body and the appearance of the symptoms
                     of the disease. It is normally not less than 24 hours.


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